|
Symbol Name ID |
Stx1b
syntaxin 1B MGI:1930705 |
| Darker colors indicate more annotations |
| Human Phenotypes | Delayed speech and language development |
Global developmental delay |
Bilateral tonic-clonic seizure |
Focal impaired awareness seizure |
Generalized non-motor (absence) seizure |
Febrile seizure (within the age range of 3 months to 6 years) |
Atonic seizure |
Tonic seizure |
| Disease(s) Associated with STX1B | ||||||||
| generalized epilepsy with febrile seizures plus 9 |
| Mouse Phenotypes | seizures |
abnormal adrenal chromaffin cell morphology |
abnormal synapse morphology |
abnormal synaptic vesicle number |
abnormal neuron physiology |
abnormal synaptic vesicle recycling |
abnormal CNS synaptic transmission |
abnormal GABA-mediated receptor currents |
abnormal excitatory postsynaptic currents |
abnormal AMPA-mediated synaptic currents |
abnormal miniature excitatory postsynaptic currents |
decreased miniature inhibitory postsynaptic current frequency |
abnormal paired-pulse inhibition |
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| Availability | Mouse Genotype | |||||||||||||
| Stx1btm1.1Sud/Stx1btm1.1Sud | ||||||||||||||
| Stx1btm1Tmis/Stx1btm1Tmis | ||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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